CUS_7203 protein (Ruminococcus albus 8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CUS_7203

Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125. (478 aa)

Predicted Functional Partners:

CUS_7204

0.996

uxaC

0.974

CUS_6335

0.864

uxuA

0.819

fbp

0.791

pfkB

0.757

pfp

0.745

CUS_7642

0.691

rpe

0.690

manA

0.689

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_6335	CUS_7203	CUS_6335	CUS_7203	Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883.	Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.	0.864
CUS_6335	CUS_7642	CUS_6335	CUS_7642	Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883.	Putative glucokinase; Identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744.	0.894
CUS_6335	fbp	CUS_6335	CUS_6833	Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883.	Firmicute fructose-1,6-bisphosphatase; Identified by match to protein family HMM PF06874.	0.864
CUS_6335	manA	CUS_6335	CUS_7643	Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883.	Mannose-6-phosphate isomerase, class I; Identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218.	0.964
CUS_6335	pfkB	CUS_6335	CUS_7063	Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883.	1-phosphofructokinase; Identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; match to protein family HMM TIGR03828; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.	0.864
CUS_6335	pfp	CUS_6335	CUS_7132	Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883.	Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.	0.803
CUS_6335	rpe	CUS_6335	CUS_6588	Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883.	Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.	0.900
CUS_7203	CUS_6335	CUS_7203	CUS_6335	Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.	Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883.	0.864
CUS_7203	CUS_7204	CUS_7203	CUS_7204	Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.	SAF domain protein; Identified by match to protein family HMM PF04295; match to protein family HMM PF08666.	0.996
CUS_7203	CUS_7642	CUS_7203	CUS_7642	Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.	Putative glucokinase; Identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744.	0.691
CUS_7203	fbp	CUS_7203	CUS_6833	Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.	Firmicute fructose-1,6-bisphosphatase; Identified by match to protein family HMM PF06874.	0.791
CUS_7203	manA	CUS_7203	CUS_7643	Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.	Mannose-6-phosphate isomerase, class I; Identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218.	0.689
CUS_7203	pfkB	CUS_7203	CUS_7063	Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.	1-phosphofructokinase; Identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168; match to protein family HMM TIGR03828; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.	0.757
CUS_7203	pfp	CUS_7203	CUS_7132	Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.	Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.	0.745
CUS_7203	rpe	CUS_7203	CUS_6588	Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.	Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.	0.690
CUS_7203	uxaC	CUS_7203	CUS_7206	Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.	Glucuronate isomerase; Identified by match to protein family HMM PF02614.	0.974
CUS_7203	uxuA	CUS_7203	CUS_7275	Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.	Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.	0.819
CUS_7204	CUS_7203	CUS_7204	CUS_7203	SAF domain protein; Identified by match to protein family HMM PF04295; match to protein family HMM PF08666.	Mannitol dehydrogenase C-terminal domain protein; Identified by match to protein family HMM PF01232; match to protein family HMM PF08125.	0.996
CUS_7204	rpe	CUS_7204	CUS_6588	SAF domain protein; Identified by match to protein family HMM PF04295; match to protein family HMM PF08666.	Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.	0.731
CUS_7204	uxaC	CUS_7204	CUS_7206	SAF domain protein; Identified by match to protein family HMM PF04295; match to protein family HMM PF08666.	Glucuronate isomerase; Identified by match to protein family HMM PF02614.	0.697