Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUS_7207Kinase, PfkB family; Identified by match to protein family HMM PF00294. (361 aa)    
Predicted Functional Partners:
eda
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to protein family HMM PF01081; match to protein family HMM TIGR01182.
 
 
 0.906
CUS_7208
Conserved domain protein.
       0.773
guaA
GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.769
CUS_6335
Putative mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883.
    
 0.734
uxaC
Glucuronate isomerase; Identified by match to protein family HMM PF02614.
 
   
 0.700
rpe
Ribulose-phosphate 3-epimerase; Identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.682
CUS_7204
SAF domain protein; Identified by match to protein family HMM PF04295; match to protein family HMM PF08666.
    
 0.627
kduD
2-deoxy-D-gluconate 3-dehydrogenase; Identified by match to protein family HMM PF00106; match to protein family HMM TIGR01832.
   
 0.618
cmk
Cytidylate kinase; Identified by match to protein family HMM PF01553; match to protein family HMM PF02224; match to protein family HMM TIGR00017.
    
  0.607
CUS_7715
Cellulase (glycosyl hydrolase family 5); Identified by match to protein family HMM PF00150; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
     
 0.595
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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