mprF protein (Ruminococcus albus 8) - STRING interaction network

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mprF

Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (342 aa)

Predicted Functional Partners:

CUS_7237

0.575

CUS_5023

0.550

CUS_5344

0.550

CUS_6460

0.531

CUS_4922

0.495

CUS_7239

0.476

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_4922	CUS_6460	CUS_4922	CUS_6460	Putative serine esterase; Identified by match to protein family HMM PF05057.	Lipid kinase, YegS/Rv2252/BmrU family; Identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147.	0.762
CUS_4922	CUS_7237	CUS_4922	CUS_7237	Putative serine esterase; Identified by match to protein family HMM PF05057.	CDP-alcohol phosphatidyltransferase; Identified by match to protein family HMM PF01066.	0.507
CUS_4922	mprF	CUS_4922	CUS_7238	Putative serine esterase; Identified by match to protein family HMM PF05057.	Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.495
CUS_5023	mprF	CUS_5023	CUS_7238	Hypothetical protein.	Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.550
CUS_5344	mprF	CUS_5344	CUS_7238	Putative phosphinothricin N-acetyltransferase; Identified by match to protein family HMM PF00583.	Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.550
CUS_6460	CUS_4922	CUS_6460	CUS_4922	Lipid kinase, YegS/Rv2252/BmrU family; Identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147.	Putative serine esterase; Identified by match to protein family HMM PF05057.	0.762
CUS_6460	mprF	CUS_6460	CUS_7238	Lipid kinase, YegS/Rv2252/BmrU family; Identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147.	Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.531
CUS_7237	CUS_4922	CUS_7237	CUS_4922	CDP-alcohol phosphatidyltransferase; Identified by match to protein family HMM PF01066.	Putative serine esterase; Identified by match to protein family HMM PF05057.	0.507
CUS_7237	mprF	CUS_7237	CUS_7238	CDP-alcohol phosphatidyltransferase; Identified by match to protein family HMM PF01066.	Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.575
CUS_7239	mprF	CUS_7239	CUS_7238	Glycosyltransferase, group 4 family; Identified by match to protein family HMM PF00953.	Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	0.476
mprF	CUS_4922	CUS_7238	CUS_4922	Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	Putative serine esterase; Identified by match to protein family HMM PF05057.	0.495
mprF	CUS_5023	CUS_7238	CUS_5023	Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	Hypothetical protein.	0.550
mprF	CUS_5344	CUS_7238	CUS_5344	Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	Putative phosphinothricin N-acetyltransferase; Identified by match to protein family HMM PF00583.	0.550
mprF	CUS_6460	CUS_7238	CUS_6460	Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	Lipid kinase, YegS/Rv2252/BmrU family; Identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147.	0.531
mprF	CUS_7237	CUS_7238	CUS_7237	Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	CDP-alcohol phosphatidyltransferase; Identified by match to protein family HMM PF01066.	0.575
mprF	CUS_7239	CUS_7238	CUS_7239	Putative membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.	Glycosyltransferase, group 4 family; Identified by match to protein family HMM PF00953.	0.476

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