fucO protein (Ruminococcus albus 8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

fucO

Lactaldehyde reductase; Identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638. (382 aa)

Predicted Functional Partners:

nifJ

0.951

CUS_4659

0.663

hymB

0.663

adhE

0.620

adhE-2

0.620

pflA

0.552

pta

0.536

pflB

0.526

CUS_4467

0.526

hisA

0.493

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_4467	CUS_4659	CUS_4467	CUS_4659	Glycine radical domain protein; Identified by match to protein family HMM PF01228.	Putative protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.	0.762
CUS_4467	adhE	CUS_4467	CUS_5484	Glycine radical domain protein; Identified by match to protein family HMM PF01228.	Aldehyde-alcohol dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.863
CUS_4467	adhE-2	CUS_4467	CUS_5687	Glycine radical domain protein; Identified by match to protein family HMM PF01228.	Aldehyde-alcohol dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.863
CUS_4467	fucO	CUS_4467	CUS_7371	Glycine radical domain protein; Identified by match to protein family HMM PF01228.	Lactaldehyde reductase; Identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638.	0.526
CUS_4467	hymB	CUS_4467	CUS_4660	Glycine radical domain protein; Identified by match to protein family HMM PF01228.	Protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00037; match to protein family HMM PF01512.	0.762
CUS_4467	nifJ	CUS_4467	CUS_6517	Glycine radical domain protein; Identified by match to protein family HMM PF01228.	Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.	0.943
CUS_4467	pflA	CUS_4467	CUS_4552	Glycine radical domain protein; Identified by match to protein family HMM PF01228.	Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	0.968
CUS_4467	pflB	CUS_4467	CUS_4465	Glycine radical domain protein; Identified by match to protein family HMM PF01228.	Formate C-acetyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02901; match to protein family HMM TIGR01255.	0.993
CUS_4467	pta	CUS_4467	CUS_6381	Glycine radical domain protein; Identified by match to protein family HMM PF01228.	Phosphate acetyltransferase; Identified by match to protein family HMM PF01515; match to protein family HMM TIGR00651.	0.633
CUS_4659	CUS_4467	CUS_4659	CUS_4467	Putative protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.	Glycine radical domain protein; Identified by match to protein family HMM PF01228.	0.762
CUS_4659	adhE	CUS_4659	CUS_5484	Putative protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.	Aldehyde-alcohol dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.942
CUS_4659	adhE-2	CUS_4659	CUS_5687	Putative protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.	Aldehyde-alcohol dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.942
CUS_4659	fucO	CUS_4659	CUS_7371	Putative protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.	Lactaldehyde reductase; Identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638.	0.663
CUS_4659	hymB	CUS_4659	CUS_4660	Putative protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.	Protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00037; match to protein family HMM PF01512.	0.999
CUS_4659	nifJ	CUS_4659	CUS_6517	Putative protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.	Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.	0.985
CUS_4659	pflA	CUS_4659	CUS_4552	Putative protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.	Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	0.415
CUS_4659	pflB	CUS_4659	CUS_4465	Putative protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.	Formate C-acetyltransferase; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF02901; match to protein family HMM TIGR01255.	0.762
CUS_4659	pta	CUS_4659	CUS_6381	Putative protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.	Phosphate acetyltransferase; Identified by match to protein family HMM PF01515; match to protein family HMM TIGR00651.	0.705
adhE	CUS_4467	CUS_5484	CUS_4467	Aldehyde-alcohol dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Glycine radical domain protein; Identified by match to protein family HMM PF01228.	0.863
adhE	CUS_4659	CUS_5484	CUS_4659	Aldehyde-alcohol dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM PF00465; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Putative protein HymB; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift.	0.942