ldh protein (Ruminococcus albus 8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ldh

L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (317 aa)

Predicted Functional Partners:

pyk

0.992

nifJ

0.989

CUS_8015

0.987

CUS_7352

0.955

CUS_7348

0.950

atpA

0.931

groL

0.922

CUS_5867

0.921

CUS_6575

0.909

CUS_6921

0.906

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_5867	CUS_6575	CUS_5867	CUS_6575	Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.	NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.	0.476
CUS_5867	CUS_6921	CUS_5867	CUS_6921	Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.	Putative aspartate transaminase.	0.580
CUS_5867	CUS_7348	CUS_5867	CUS_7348	Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.	Putative aconitate hydratase.	0.774
CUS_5867	CUS_7352	CUS_5867	CUS_7352	Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.	Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00127; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.923
CUS_5867	CUS_8015	CUS_5867	CUS_8015	Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.	Citrate (Si)-synthase; Identified by match to protein family HMM PF00285.	0.976
CUS_5867	atpA	CUS_5867	CUS_7415	Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.	ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.	0.795
CUS_5867	groL	CUS_5867	CUS_5731	Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.	Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.493
CUS_5867	ldh	CUS_5867	CUS_7535	Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.	0.921
CUS_5867	nifJ	CUS_5867	CUS_6517	Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.	Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.	0.975
CUS_5867	pyk	CUS_5867	CUS_6706	Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.	Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.	0.419
CUS_6575	CUS_5867	CUS_6575	CUS_5867	NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.	Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.	0.476
CUS_6575	CUS_6921	CUS_6575	CUS_6921	NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.	Putative aspartate transaminase.	0.646
CUS_6575	CUS_7348	CUS_6575	CUS_7348	NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.	Putative aconitate hydratase.	0.455
CUS_6575	CUS_7352	CUS_6575	CUS_7352	NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.	Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00127; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.478
CUS_6575	CUS_8015	CUS_6575	CUS_8015	NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.	Citrate (Si)-synthase; Identified by match to protein family HMM PF00285.	0.885
CUS_6575	groL	CUS_6575	CUS_5731	NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.	Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.474
CUS_6575	ldh	CUS_6575	CUS_7535	NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.	0.909
CUS_6575	nifJ	CUS_6575	CUS_6517	NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.	Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.	0.943
CUS_6575	pyk	CUS_6575	CUS_6706	NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF03949.	Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.	0.963
CUS_6921	CUS_5867	CUS_6921	CUS_5867	Putative aspartate transaminase.	Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.	0.580