Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUS_7567Saccharopine dehydrogenase; Identified by match to protein family HMM PF03435. (400 aa)    
Predicted Functional Partners:
nspC
Carboxynorspermidine decarboxylase; Identified by match to protein family HMM PF00278; match to protein family HMM TIGR01047.
 
 
 0.974
speA
Arginine 2-monooxygenase; Identified by match to protein family HMM PF01053; match to protein family HMM PF01212; match to protein family HMM PF01276; match to protein family HMM PF03711.
 
  
  0.931
speB-2
Agmatinase; Identified by match to protein family HMM PF00491; match to protein family HMM TIGR01230; Belongs to the arginase family.
   
 0.891
speB
Agmatinase; Identified by match to protein family HMM PF00491; match to protein family HMM TIGR01230; Belongs to the arginase family.
   
 0.717
folE
Putative GTP cyclohydrolase I; Identified by match to protein family HMM PF01227.
   
   0.712
CUS_7919
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583.
   
 
  0.699
CUS_5851
Orn/Lys/Arg decarboxylase, major domain protein; Identified by match to protein family HMM PF01276.
    
  0.578
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. Belongs to the diaminopimelate epimerase family.
  
 
 0.559
CUS_5644
Putative linear gramicidin synthetase LgrC; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM TIGR01733.
  
 
 0.521
CUS_6122
AMP-binding enzyme; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF01553; match to protein family HMM TIGR01733; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.521
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.