Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CUS_7653Carboxylesterase; Identified by match to protein family HMM PF00135; Belongs to the type-B carboxylesterase/lipase family. (502 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
  0.878
CUS_7654
Glycosyl hydrolase, family 43; Identified by match to protein family HMM PF04616; Belongs to the glycosyl hydrolase 43 family.
 
   
 0.848
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
     
  0.676
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
     
  0.652
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
   0.554
CUS_4551
Glycosyl hydrolase, family 31; Identified by match to protein family HMM PF01055; Belongs to the glycosyl hydrolase 31 family.
  
  
 0.539
CUS_5670
Identified by match to protein family HMM PF08929.
  
 
 0.523
CUS_7652
HAD hydrolase, family IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509.
  
    0.483
CUS_5087
Hypothetical protein; Identified by glimmer; putative.
  
 
   0.481
CUS_5646
AMP-binding enzyme; Identified by match to protein family HMM PF00106; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF08659.
   
 0.481
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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