Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
CUS_7692Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF00990. (282 aa)    
Predicted Functional Partners:
rpoA
RNA polymerase, alpha subunit C-terminal domain protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.908
nifJ
Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
     
 0.842
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.825
CUS_5811
Putative DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.808
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.808
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.775
CUS_6221
RNA polymerase sigma factor, sigma-70 family; Identified by match to protein family HMM TIGR02937.
    
 
 0.775
CUS_7547
Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF02311; match to protein family HMM PF07883.
 
 
 0.700
CUS_7182
Transcriptional regulator, AraC family; Identified by match to protein family HMM PF00165; match to protein family HMM PF02311.
 
 
 
 0.699
CUS_7693
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293; Belongs to the Nudix hydrolase family.
       0.697
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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