Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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CUS_7768Putative stage III sporulation protein E; Identified by match to protein family HMM PF01580; match to protein family HMM PF09397; Belongs to the FtsK/SpoIIIE/SftA family. (888 aa)    
Predicted Functional Partners:
CUS_7769
Metallo-beta-lactamase domain protein; Identified by match to protein family HMM PF00753.
 
  
 0.833
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
  
 0.821
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.801
CUS_6557
POTRA domain protein, FtsQ-type; Essential cell division protein.
   
 
 0.801
CUS_7770
Hypothetical protein.
       0.783
CUS_6548
Penicillin-binding protein, transpeptidase domain protein; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793.
 
 
 
 0.742
CUS_5176
Putative stage 0 sporulation protein J; Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family.
  
  
 0.740
CUS_5178
Putative nucleoid occlusion protein; Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family.
  
  
 0.739
cmk
Cytidylate kinase; Identified by match to protein family HMM PF01553; match to protein family HMM PF02224; match to protein family HMM TIGR00017.
  
    0.711
CUS_6552
Putative cell division protein FtsW; Identified by match to protein family HMM PF01098; Belongs to the SEDS family.
 
  
 0.701
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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