Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CUS_7777HAD hydrolase, family IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549. (223 aa)    
Predicted Functional Partners:
CUS_5645
Beta-ketoacyl synthase, N-terminal domain protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF02801.
   
 
  0.864
guaA
GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.852
CUS_7778
Identified by match to protein family HMM PF01987; match to protein family HMM TIGR00266.
       0.682
CUS_6887
Alpha amylase, catalytic domain protein; Identified by match to protein family HMM PF00128.
 
 
 0.547
CUS_7776
Identified by match to protein family HMM PF01170.
       0.479
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
  
 0.447
CUS_7652
HAD hydrolase, family IA, variant 3; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509.
 
 
 0.437
CUS_7779
DNA-binding helix-turn-helix protein; Identified by match to protein family HMM PF01381.
       0.426
CUS_5848
Putative glycerate dehydrogenase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
  0.402
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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