STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CUS_7790Putative ATP-dependent nuclease subunit A; ATP-dependent DNA helicase. (1234 aa)    
Predicted Functional Partners:
CUS_7789
Putative ATP-dependent nuclease subunit B; ATP-dependent DNA helicase.
 
 
 0.999
recD2
Helicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily.
  
 
 0.839
CUS_4331
Hypothetical protein; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by glimmer; putative.
  
 
 0.790
CUS_5930
Relaxase/mobilization nuclease domain protein; Identified by match to protein family HMM PF03432.
  
 
 0.790
CUS_7462
Hypothetical protein.
  
 
 0.790
CUS_7739
Conserved domain protein.
  
 
 0.790
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.732
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.709
CUS_6352
Identified by match to protein family HMM PF04816.
 
     0.676
CUS_6152
Exonuclease SbcCD, C subunit; Identified by match to protein family HMM PF02463.
 
  
 0.617
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.