thrC protein (Ruminococcus albus 8) - STRING interaction network

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thrC

Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260. (497 aa)

Predicted Functional Partners:

thrB

0.998

CUS_6412

0.973

ilvA

0.943

serC

0.914

thrH

0.889

CUS_7760

0.824

leuD

0.739

CUS_7787

0.704

ylqF

0.704

rnhB

0.704

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_6412	CUS_7760	CUS_6412	CUS_7760	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	Putative aspartate kinase; Identified by match to protein family HMM PF01842; Belongs to the aspartokinase family.	0.958
CUS_6412	CUS_7787	CUS_6412	CUS_7787	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	0.963
CUS_6412	ilvA	CUS_6412	CUS_6532	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.909
CUS_6412	serC	CUS_6412	CUS_5224	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.	0.425
CUS_6412	thrB	CUS_6412	CUS_6282	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.	0.994
CUS_6412	thrC	CUS_6412	CUS_7799	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260.	0.973
CUS_6412	thrH	CUS_6412	CUS_6866	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR02137.	0.889
CUS_7760	CUS_6412	CUS_7760	CUS_6412	Putative aspartate kinase; Identified by match to protein family HMM PF01842; Belongs to the aspartokinase family.	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	0.958
CUS_7760	CUS_7787	CUS_7760	CUS_7787	Putative aspartate kinase; Identified by match to protein family HMM PF01842; Belongs to the aspartokinase family.	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	0.950
CUS_7760	ilvA	CUS_7760	CUS_6532	Putative aspartate kinase; Identified by match to protein family HMM PF01842; Belongs to the aspartokinase family.	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.922
CUS_7760	thrB	CUS_7760	CUS_6282	Putative aspartate kinase; Identified by match to protein family HMM PF01842; Belongs to the aspartokinase family.	Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.	0.914
CUS_7760	thrC	CUS_7760	CUS_7799	Putative aspartate kinase; Identified by match to protein family HMM PF01842; Belongs to the aspartokinase family.	Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260.	0.824
CUS_7760	thrH	CUS_7760	CUS_6866	Putative aspartate kinase; Identified by match to protein family HMM PF01842; Belongs to the aspartokinase family.	Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR02137.	0.533
CUS_7787	CUS_6412	CUS_7787	CUS_6412	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF03447.	0.963
CUS_7787	CUS_7760	CUS_7787	CUS_7760	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Putative aspartate kinase; Identified by match to protein family HMM PF01842; Belongs to the aspartokinase family.	0.950
CUS_7787	ilvA	CUS_7787	CUS_6532	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.	0.947
CUS_7787	serC	CUS_7787	CUS_5224	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.	0.433
CUS_7787	thrB	CUS_7787	CUS_6282	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.	0.932
CUS_7787	thrC	CUS_7787	CUS_7799	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Threonine synthase; Identified by match to protein family HMM PF00291; match to protein family HMM TIGR00260.	0.704
CUS_7787	thrH	CUS_7787	CUS_6866	Putative methionine synthase; Identified by match to protein family HMM PF00809; match to protein family HMM PF02310; match to protein family HMM PF02574; match to protein family HMM PF02607.	Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR02137.	0.900