| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CUS_5234 | nadD | CUS_5234 | CUS_4625 | Putative NAD(P)(+) transhydrogenase (B-specific), subunit PntAB. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.750 |
| CUS_5234 | nadK | CUS_5234 | CUS_7822 | Putative NAD(P)(+) transhydrogenase (B-specific), subunit PntAB. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.879 |
| CUS_5234 | npdA | CUS_5234 | CUS_7667 | Putative NAD(P)(+) transhydrogenase (B-specific), subunit PntAB. | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.714 |
| CUS_7819 | argR | CUS_7819 | CUS_7823 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.785 |
| CUS_7819 | dxs | CUS_7819 | CUS_7820 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.795 |
| CUS_7819 | nadK | CUS_7819 | CUS_7822 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.819 |
| CUS_7819 | recN | CUS_7819 | CUS_7824 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.792 |
| CUS_7819 | rrmJ | CUS_7819 | CUS_7821 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Ribosomal RNA large subunit methyltransferase J; Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478. | 0.913 |
| CUS_7819 | xseB | CUS_7819 | CUS_7818 | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.937 |
| argR | CUS_7819 | CUS_7823 | CUS_7819 | Arginine repressor; Regulates arginine biosynthesis genes. | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 0.785 |
| argR | dxs | CUS_7823 | CUS_7820 | Arginine repressor; Regulates arginine biosynthesis genes. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.793 |
| argR | nadD | CUS_7823 | CUS_4625 | Arginine repressor; Regulates arginine biosynthesis genes. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.415 |
| argR | nadK | CUS_7823 | CUS_7822 | Arginine repressor; Regulates arginine biosynthesis genes. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.850 |
| argR | recN | CUS_7823 | CUS_7824 | Arginine repressor; Regulates arginine biosynthesis genes. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.871 |
| argR | rrmJ | CUS_7823 | CUS_7821 | Arginine repressor; Regulates arginine biosynthesis genes. | Ribosomal RNA large subunit methyltransferase J; Identified by match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478. | 0.851 |
| argR | xseB | CUS_7823 | CUS_7818 | Arginine repressor; Regulates arginine biosynthesis genes. | Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.767 |
| dxs | CUS_7819 | CUS_7820 | CUS_7819 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Polyprenyl synthetase; Identified by match to protein family HMM PF00348; Belongs to the FPP/GGPP synthase family. | 0.795 |
| dxs | argR | CUS_7820 | CUS_7823 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Arginine repressor; Regulates arginine biosynthesis genes. | 0.793 |
| dxs | nadK | CUS_7820 | CUS_7822 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.893 |
| dxs | recN | CUS_7820 | CUS_7824 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.805 |