Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUS_7835CotH protein; Identified by match to protein family HMM PF08757. (504 aa)    
Predicted Functional Partners:
CUS_6968
Dockerin type I repeat protein; Identified by match to protein family HMM PF00404.
  
     0.685
CUS_7832
Phosphoribosylaminoimidazole carboxylase; Identified by match to protein family HMM PF00731.
       0.671
larC
TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
       0.671
CUS_7834
Flavin reductase; Identified by match to protein family HMM PF03358.
       0.671
guaA
GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.
     
  0.656
CUS_5681
Mannan endo-1,4-beta-mannosidase domain protein; Identified by match to protein family HMM PF02156; Belongs to the glycosyl hydrolase 26 family.
  
     0.642
CUS_5843
Cellulase (glycosyl hydrolase family 5); Identified by match to protein family HMM PF00150; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.637
CUS_6389
Cellulase (glycosyl hydrolase family 5); Identified by match to protein family HMM PF00150.
  
     0.594
CUS_7090
Putative endoglucanase C; Identified by match to protein family HMM PF00759; match to protein family HMM PF02018; match to protein family HMM PF02927.
  
     0.592
CUS_5279
Dockerin type I repeat protein; Identified by match to protein family HMM PF00404; match to protein family HMM PF02156; Belongs to the glycosyl hydrolase 26 family.
  
     0.587
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.