CUS_7952 protein (Ruminococcus albus 8) - STRING interaction network

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CUS_7952

DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986. (661 aa)

Predicted Functional Partners:

CUS_7953

0.991

gyrA

0.972

CUS_7951

0.762

recQ

0.716

CUS_4587

0.679

truB

0.642

dnaN

0.599

polA

0.568

CUS_5645

0.549

recF

0.522

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_4587	CUS_7952	CUS_4587	CUS_7952	Helicase C-terminal domain protein; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271.	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	0.679
CUS_4587	dnaN	CUS_4587	CUS_4974	Helicase C-terminal domain protein; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.920
CUS_4587	polA	CUS_4587	CUS_6380	Helicase C-terminal domain protein; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271.	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.970
CUS_4587	recQ	CUS_4587	CUS_5293	Helicase C-terminal domain protein; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271.	ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389.	0.814
CUS_5645	CUS_7952	CUS_5645	CUS_7952	Beta-ketoacyl synthase, N-terminal domain protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF02801.	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	0.549
CUS_5645	CUS_7953	CUS_5645	CUS_7953	Beta-ketoacyl synthase, N-terminal domain protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF02801.	DNA gyrase/topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521; match to protein family HMM PF03989.	0.459
CUS_5645	gyrA	CUS_5645	CUS_4965	Beta-ketoacyl synthase, N-terminal domain protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF02801.	DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.459
CUS_5645	polA	CUS_5645	CUS_6380	Beta-ketoacyl synthase, N-terminal domain protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF02801.	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.628
CUS_7951	CUS_7952	CUS_7951	CUS_7952	Hypothetical protein; Identified by glimmer; putative.	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	0.762
CUS_7951	CUS_7953	CUS_7951	CUS_7953	Hypothetical protein; Identified by glimmer; putative.	DNA gyrase/topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521; match to protein family HMM PF03989.	0.622
CUS_7952	CUS_4587	CUS_7952	CUS_4587	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	Helicase C-terminal domain protein; Identified by match to protein family HMM PF00176; match to protein family HMM PF00271.	0.679
CUS_7952	CUS_5645	CUS_7952	CUS_5645	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	Beta-ketoacyl synthase, N-terminal domain protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF02801.	0.549
CUS_7952	CUS_7951	CUS_7952	CUS_7951	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	Hypothetical protein; Identified by glimmer; putative.	0.762
CUS_7952	CUS_7953	CUS_7952	CUS_7953	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	DNA gyrase/topoisomerase IV, A subunit; Identified by match to protein family HMM PF00521; match to protein family HMM PF03989.	0.991
CUS_7952	dnaN	CUS_7952	CUS_4974	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.599
CUS_7952	gyrA	CUS_7952	CUS_4965	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.	0.972
CUS_7952	polA	CUS_7952	CUS_6380	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.568
CUS_7952	recF	CUS_7952	CUS_4972	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.	0.522
CUS_7952	recQ	CUS_7952	CUS_5293	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM PF09382; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389.	0.716
CUS_7952	truB	CUS_7952	CUS_7298	DNA gyrase, B subunit, C-terminal domain protein; Identified by match to protein family HMM PF00204; match to protein family HMM PF00986.	tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.	0.642