STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIVBSpoIVB peptidase; Identified by match to protein family HMM PF05580; match to protein family HMM TIGR02860. (400 aa)    
Predicted Functional Partners:
CUS_4878
Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
   
 0.936
sigK
RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.852
CUS_5685
Sporulation initiation factor Spo0A C-terminal domain protein; Identified by match to protein family HMM PF08769.
 
   
 0.846
spoIIP
Stage II sporulation protein P; Identified by match to protein family HMM PF07454; match to protein family HMM TIGR02867.
  
   
 0.833
gpr
Putative GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
    0.810
spoIVA
Stage IV sporulation protein A; Identified by match to protein family HMM PF09547; match to protein family HMM TIGR02836.
  
   
 0.798
spoIIID
Stage III sporulation protein D.
  
   
 0.798
yabP
Sporulation protein YabP; Identified by match to protein family HMM PF07873; match to protein family HMM TIGR02892.
  
   
 0.791
CUS_7808
Stage III sporulation protein AC; Identified by match to protein family HMM PF06686; match to protein family HMM TIGR02848.
 
     0.787
CUS_7806
Putative stage III sporulation protein AA.
 
     0.786
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.