CUS_8014 protein (Ruminococcus albus 8) - STRING interaction network

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Score

CUS_8014

Peptidase, M48 family; Identified by match to protein family HMM PF01435. (447 aa)

Predicted Functional Partners:

CUS_5719

0.772

CUS_8013

0.639

grpE

0.598

CUS_6314

0.503

dnaJ

0.500

CUS_8015

0.483

CUS_5720

0.467

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_5719	CUS_5720	CUS_5719	CUS_5720	Hypothetical protein; Identified by glimmer; putative.	Conserved domain protein.	0.912
CUS_5719	CUS_6314	CUS_5719	CUS_6314	Hypothetical protein; Identified by glimmer; putative.	Asparagine synthase; Identified by match to protein family HMM PF00733.	0.636
CUS_5719	CUS_8014	CUS_5719	CUS_8014	Hypothetical protein; Identified by glimmer; putative.	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	0.772
CUS_5719	dnaJ	CUS_5719	CUS_6701	Hypothetical protein; Identified by glimmer; putative.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.500
CUS_5719	grpE	CUS_5719	CUS_6703	Hypothetical protein; Identified by glimmer; putative.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.556
CUS_5720	CUS_5719	CUS_5720	CUS_5719	Conserved domain protein.	Hypothetical protein; Identified by glimmer; putative.	0.912
CUS_5720	CUS_8014	CUS_5720	CUS_8014	Conserved domain protein.	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	0.467
CUS_6314	CUS_5719	CUS_6314	CUS_5719	Asparagine synthase; Identified by match to protein family HMM PF00733.	Hypothetical protein; Identified by glimmer; putative.	0.636
CUS_6314	CUS_8014	CUS_6314	CUS_8014	Asparagine synthase; Identified by match to protein family HMM PF00733.	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	0.503
CUS_8013	CUS_8014	CUS_8013	CUS_8014	Conserved domain protein.	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	0.639
CUS_8014	CUS_5719	CUS_8014	CUS_5719	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	Hypothetical protein; Identified by glimmer; putative.	0.772
CUS_8014	CUS_5720	CUS_8014	CUS_5720	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	Conserved domain protein.	0.467
CUS_8014	CUS_6314	CUS_8014	CUS_6314	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	Asparagine synthase; Identified by match to protein family HMM PF00733.	0.503
CUS_8014	CUS_8013	CUS_8014	CUS_8013	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	Conserved domain protein.	0.639
CUS_8014	CUS_8015	CUS_8014	CUS_8015	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	Citrate (Si)-synthase; Identified by match to protein family HMM PF00285.	0.483
CUS_8014	dnaJ	CUS_8014	CUS_6701	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.500
CUS_8014	grpE	CUS_8014	CUS_6703	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]	0.598
CUS_8015	CUS_8014	CUS_8015	CUS_8014	Citrate (Si)-synthase; Identified by match to protein family HMM PF00285.	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	0.483
dnaJ	CUS_5719	CUS_6701	CUS_5719	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	Hypothetical protein; Identified by glimmer; putative.	0.500
dnaJ	CUS_8014	CUS_6701	CUS_8014	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	Peptidase, M48 family; Identified by match to protein family HMM PF01435.	0.500