Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CUS_8015Citrate (Si)-synthase; Identified by match to protein family HMM PF00285. (448 aa)    
Predicted Functional Partners:
CUS_7348
Putative aconitate hydratase.
 
 0.994
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.987
CUS_5867
Putative succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910.
 
 0.976
CUS_5868
Putative succinate dehydrogenase iron-sulfur subunit; Identified by match to protein family HMM TIGR00384.
  
 0.954
nifJ
Pyruvate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176.
    
 0.942
aepX
Phosphoenolpyruvate mutase; Identified by match to protein family HMM PF01467; match to protein family HMM TIGR00125; match to protein family HMM TIGR02320.
  
 0.935
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
 0.930
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
   
 0.927
CUS_5922
AMP-binding enzyme; Identified by match to protein family HMM PF00501.
  
 0.921
CUS_7143
Hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; Identified by match to protein family HMM PF05681; match to protein family HMM TIGR00722.
  
 
 0.916
Your Current Organism:
Ruminococcus albus 8
NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8
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