CUS_8089 protein (Ruminococcus albus 8) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CUS_8089

Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. (194 aa)

Predicted Functional Partners:

folC-2

0.650

CUS_8091

0.521

CUS_8088

0.501

rdgB

0.445

Your Current Organism:

Ruminococcus albus 8

NCBI taxonomy Id: 246199
Other names: R. albus 8, Ruminococcus albus str. 8

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUS_8088	CUS_8089	CUS_8088	CUS_8089	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM TIGR00254.	Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	0.501
CUS_8088	folC-2	CUS_8088	CUS_8090	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM TIGR00254.	Bifunctional protein FolC; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.	0.425
CUS_8089	CUS_8088	CUS_8089	CUS_8088	Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM TIGR00254.	0.501
CUS_8089	CUS_8091	CUS_8089	CUS_8091	Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	Conserved domain protein.	0.521
CUS_8089	folC-2	CUS_8089	CUS_8090	Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	Bifunctional protein FolC; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.	0.650
CUS_8089	rdgB	CUS_8089	CUS_7437	Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.445
CUS_8091	CUS_8089	CUS_8091	CUS_8089	Conserved domain protein.	Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	0.521
CUS_8091	folC-2	CUS_8091	CUS_8090	Conserved domain protein.	Bifunctional protein FolC; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.	0.630
folC-2	CUS_8088	CUS_8090	CUS_8088	Bifunctional protein FolC; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.	Diguanylate cyclase (GGDEF) domain protein; Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF08447; match to protein family HMM TIGR00254.	0.425
folC-2	CUS_8089	CUS_8090	CUS_8089	Bifunctional protein FolC; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.	Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	0.650
folC-2	CUS_8091	CUS_8090	CUS_8091	Bifunctional protein FolC; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.	Conserved domain protein.	0.630
folC-2	rdgB	CUS_8090	CUS_7437	Bifunctional protein FolC; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.	Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.404
rdgB	CUS_8089	CUS_7437	CUS_8089	Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040.	0.445
rdgB	folC-2	CUS_7437	CUS_8090	Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Bifunctional protein FolC; Identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.	0.404