STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO0023Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293; Belongs to the Nudix hydrolase family. (150 aa)    
Predicted Functional Partners:
hslO
Chaperonin, 33 kDa; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family.
 
     0.705
SPO0026
Identified by match to protein family HMM PF01743; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
   
 
 0.694
nnrD
YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
  
 0.626
SPO0025
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.
  
  
 0.594
SPO0665
SlyX protein, putative; Identified by similarity to SP:Q89SJ8.
  
     0.572
SPO0338
Cell division permease protein FtsX, putative; Identified by match to protein family HMM PF02687.
  
   
 0.533
SPO3099
Hypothetical protein; Identified by similarity to GB:BAC46414.1.
  
     0.485
SPO3540
Hypothetical protein; 'Novel gene detected by proteogenomics, SPO_PG032; identified in over 20 other Roseobacter strains'.
 
     0.479
SPO3632
Hypothetical protein; Identified by similarity to GB:BAC45762.1.
  
     0.457
SPO1769
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.453
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.