STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO0052ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (263 aa)    
Predicted Functional Partners:
SPO0053
ABC transporter, permease protein; Identified by match to protein family HMM PF00528.
 0.995
SPO0050
ABC transporter, periplasmic substrate-binding protein; Assignment based partly on membership in ABC transporter gene cluster.
 
 0.993
SPO0051
TENA/THI-4 family protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.
 
    0.933
modB
Molybdate ABC transporter, permease protein; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
    
 0.806
SPO0049
Thiamine biosynthesis protein ThiF; Identified by match to protein family HMM PF00899; match to protein family HMM PF05237.
 
  
 0.759
thiS
Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.
 
    0.757
SPO3618
Sulfonate ABC transporter, permease protein, putative; Identified by similarity to SP:P75851; similarity to SP:Q47539; match to protein family HMM PF00528.
 
 0.730
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
 
    0.725
SPO0046
Thiamine biosynthesis oxidoreductase ThiO, putative; Identified by match to protein family HMM PF01266.
 
    0.710
SPO1787
ABC transporter, permease protein; Identified by match to protein family HMM PF00528.
 
 0.699
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
Server load: low (22%) [HD]