STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (331 aa)    
Predicted Functional Partners:
SPO3893
Membrane protein, putative; Identified by match to protein family HMM PF03653.
 
  
 0.955
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.947
cyoE
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
     
 0.935
SPO0465
Pyridoxamine 5'-phosphate oxidase family protein; Identified by match to protein family HMM PF01243.
     
 0.906
hemF
Coproporphyrinogen III oxidase, aerobic; Identified by match to protein family HMM PF01218.
 
  
 0.787
SPO0072
Hypothetical protein; Identified by similarity to GB:CAE26039.1.
  
  
 0.685
SPO2335
ABC transporter, ATP-binding/permease protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664.
  
 
 0.654
hpf
Ribosomal subunit interface protein, putative; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
   
  
 0.640
hemB
Porphobilinogen synthase; Identified by similarity to SP:Q59643; match to protein family HMM PF00490; Belongs to the ALAD family.
 
  
 0.635
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.617
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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