| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO0079 | SPO0083 | SPO0079 | SPO0083 | ABC transporter, ATP-binding protein; Identified by similarity to GB:AAM48706.1; match to protein family HMM PF00005. | Exonuclease, putative; Identified by match to protein family HMM PF01612. | 0.836 |
| SPO0079 | betB | SPO0079 | SPO0084 | ABC transporter, ATP-binding protein; Identified by similarity to GB:AAM48706.1; match to protein family HMM PF00005. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.417 |
| SPO0079 | kdsD | SPO0079 | SPO0082 | ABC transporter, ATP-binding protein; Identified by similarity to GB:AAM48706.1; match to protein family HMM PF00005. | Arabinose 5-phosphate isomerase; Identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.965 |
| SPO0083 | SPO0079 | SPO0083 | SPO0079 | Exonuclease, putative; Identified by match to protein family HMM PF01612. | ABC transporter, ATP-binding protein; Identified by similarity to GB:AAM48706.1; match to protein family HMM PF00005. | 0.836 |
| SPO0083 | betB | SPO0083 | SPO0084 | Exonuclease, putative; Identified by match to protein family HMM PF01612. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.478 |
| SPO0083 | kdsD | SPO0083 | SPO0082 | Exonuclease, putative; Identified by match to protein family HMM PF01612. | Arabinose 5-phosphate isomerase; Identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.854 |
| SPO0085 | betB | SPO0085 | SPO0084 | Hypothetical protein; Identified by similarity to GB:CAE29577.1. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.511 |
| SPO2609 | betB | SPO2609 | SPO0084 | Alcohol dehydrogenase, iron-containing; Identified by match to protein family HMM PF00465. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.457 |
| betA | betB | SPO1088 | SPO0084 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.946 |
| betA | betI | SPO1088 | SPO1082 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | 0.566 |
| betA | betI-2 | SPO1088 | SPO1086 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Transcriptional regulator, TetR family; Repressor involved in choline regulation of the bet genes. | 0.688 |
| betB | SPO0079 | SPO0084 | SPO0079 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | ABC transporter, ATP-binding protein; Identified by similarity to GB:AAM48706.1; match to protein family HMM PF00005. | 0.417 |
| betB | SPO0083 | SPO0084 | SPO0083 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Exonuclease, putative; Identified by match to protein family HMM PF01612. | 0.478 |
| betB | SPO0085 | SPO0084 | SPO0085 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Hypothetical protein; Identified by similarity to GB:CAE29577.1. | 0.511 |
| betB | SPO2609 | SPO0084 | SPO2609 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Alcohol dehydrogenase, iron-containing; Identified by match to protein family HMM PF00465. | 0.457 |
| betB | betA | SPO0084 | SPO1088 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.946 |
| betB | betI | SPO0084 | SPO1082 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | 0.454 |
| betB | betI-2 | SPO0084 | SPO1086 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Transcriptional regulator, TetR family; Repressor involved in choline regulation of the bet genes. | 0.667 |
| betB | fmt | SPO0084 | SPO3216 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.900 |
| betB | kdsD | SPO0084 | SPO0082 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Arabinose 5-phosphate isomerase; Identified by similarity to SP:P45395; match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.522 |