node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SPO0091 | SPO0092 | SPO0091 | SPO0092 | Rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | 0.591 |
SPO0091 | nnrD | SPO0091 | SPO2293 | Rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.467 |
SPO0091 | pncA | SPO0091 | SPO0093 | Rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | Pyrazinamidase/nicotinamidase; Identified by similarity to SP:P21369; match to protein family HMM PF00857. | 0.644 |
SPO0091 | pncB | SPO0091 | SPO0095 | Rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.556 |
SPO0091 | rluA | SPO0091 | SPO3392 | Rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | Ribosomal large subunit pseudouridine synthase A; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.530 |
SPO0091 | rluC | SPO0091 | SPO0516 | Rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.676 |
SPO0092 | SPO0091 | SPO0092 | SPO0091 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | Rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | 0.591 |
SPO0092 | pncA | SPO0092 | SPO0093 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | Pyrazinamidase/nicotinamidase; Identified by similarity to SP:P21369; match to protein family HMM PF00857. | 0.561 |
SPO0092 | pncB | SPO0092 | SPO0095 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.436 |
nnrD | SPO0091 | SPO2293 | SPO0091 | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | Rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | 0.467 |
nnrD | pncA | SPO2293 | SPO0093 | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | Pyrazinamidase/nicotinamidase; Identified by similarity to SP:P21369; match to protein family HMM PF00857. | 0.419 |
pncA | SPO0091 | SPO0093 | SPO0091 | Pyrazinamidase/nicotinamidase; Identified by similarity to SP:P21369; match to protein family HMM PF00857. | Rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | 0.644 |
pncA | SPO0092 | SPO0093 | SPO0092 | Pyrazinamidase/nicotinamidase; Identified by similarity to SP:P21369; match to protein family HMM PF00857. | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | 0.561 |
pncA | nnrD | SPO0093 | SPO2293 | Pyrazinamidase/nicotinamidase; Identified by similarity to SP:P21369; match to protein family HMM PF00857. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.419 |
pncA | pncB | SPO0093 | SPO0095 | Pyrazinamidase/nicotinamidase; Identified by similarity to SP:P21369; match to protein family HMM PF00857. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.995 |
pncB | SPO0091 | SPO0095 | SPO0091 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | 0.556 |
pncB | SPO0092 | SPO0095 | SPO0092 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. | 0.436 |
pncB | pncA | SPO0095 | SPO0093 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Pyrazinamidase/nicotinamidase; Identified by similarity to SP:P21369; match to protein family HMM PF00857. | 0.995 |
rluA | SPO0091 | SPO3392 | SPO0091 | Ribosomal large subunit pseudouridine synthase A; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | 0.530 |
rluC | SPO0091 | SPO0516 | SPO0091 | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Rhodanese-like domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | 0.676 |