| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO0007 | glpK | SPO0007 | SPO0104 | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.698 |
| SPO0369 | glpD | SPO0369 | SPO0732 | Acyltransferase family protein; Identified by similarity to SP:P00482; match to protein family HMM PF01553. | Aerobic glycerol-3-phosphate dehydrogenase; Identified by similarity to SP:P13035; match to protein family HMM PF01266; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.919 |
| SPO0369 | glpK | SPO0369 | SPO0104 | Acyltransferase family protein; Identified by similarity to SP:P00482; match to protein family HMM PF01553. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.917 |
| SPO0369 | plsY | SPO0369 | SPO0283 | Acyltransferase family protein; Identified by similarity to SP:P00482; match to protein family HMM PF01553. | Putative protein TIGR00023; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.935 |
| SPO0621 | SPO1487 | SPO0621 | SPO1487 | Ankrin repeat protein. | Membrane protein, putative. | 0.474 |
| SPO0621 | apqZ | SPO0621 | SPO0970 | Ankrin repeat protein. | Aquaporin Z; Identified by similarity to SP:P48838; match to protein family HMM PF00230; match to protein family HMM TIGR00861; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.401 |
| SPO0621 | glpK | SPO0621 | SPO0104 | Ankrin repeat protein. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.741 |
| SPO1487 | SPO0621 | SPO1487 | SPO0621 | Membrane protein, putative. | Ankrin repeat protein. | 0.474 |
| SPO1487 | glpD | SPO1487 | SPO0732 | Membrane protein, putative. | Aerobic glycerol-3-phosphate dehydrogenase; Identified by similarity to SP:P13035; match to protein family HMM PF01266; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.799 |
| SPO1487 | glpK | SPO1487 | SPO0104 | Membrane protein, putative. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.859 |
| apqZ | SPO0621 | SPO0970 | SPO0621 | Aquaporin Z; Identified by similarity to SP:P48838; match to protein family HMM PF00230; match to protein family HMM TIGR00861; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Ankrin repeat protein. | 0.401 |
| apqZ | glpD | SPO0970 | SPO0732 | Aquaporin Z; Identified by similarity to SP:P48838; match to protein family HMM PF00230; match to protein family HMM TIGR00861; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aerobic glycerol-3-phosphate dehydrogenase; Identified by similarity to SP:P13035; match to protein family HMM PF01266; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.861 |
| apqZ | glpK | SPO0970 | SPO0104 | Aquaporin Z; Identified by similarity to SP:P48838; match to protein family HMM PF00230; match to protein family HMM TIGR00861; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.915 |
| glpD | SPO0369 | SPO0732 | SPO0369 | Aerobic glycerol-3-phosphate dehydrogenase; Identified by similarity to SP:P13035; match to protein family HMM PF01266; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | Acyltransferase family protein; Identified by similarity to SP:P00482; match to protein family HMM PF01553. | 0.919 |
| glpD | SPO1487 | SPO0732 | SPO1487 | Aerobic glycerol-3-phosphate dehydrogenase; Identified by similarity to SP:P13035; match to protein family HMM PF01266; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | Membrane protein, putative. | 0.799 |
| glpD | apqZ | SPO0732 | SPO0970 | Aerobic glycerol-3-phosphate dehydrogenase; Identified by similarity to SP:P13035; match to protein family HMM PF01266; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | Aquaporin Z; Identified by similarity to SP:P48838; match to protein family HMM PF00230; match to protein family HMM TIGR00861; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.861 |
| glpD | glpK | SPO0732 | SPO0104 | Aerobic glycerol-3-phosphate dehydrogenase; Identified by similarity to SP:P13035; match to protein family HMM PF01266; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.999 |
| glpD | plsY | SPO0732 | SPO0283 | Aerobic glycerol-3-phosphate dehydrogenase; Identified by similarity to SP:P13035; match to protein family HMM PF01266; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | Putative protein TIGR00023; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.917 |
| glpD | xylA | SPO0732 | SPO0856 | Aerobic glycerol-3-phosphate dehydrogenase; Identified by similarity to SP:P13035; match to protein family HMM PF01266; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. | Xylose isomerase; Identified by match to protein family HMM PF00259; Belongs to the xylose isomerase family. | 0.611 |
| glpK | SPO0007 | SPO0104 | SPO0007 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.698 |