STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO0154NAD(P)H dehydrogenase, quinone family; Identified by similarity to SP:P45245; match to protein family HMM PF02525. (197 aa)    
Predicted Functional Partners:
SPO1424
Glutathione-regulated potassium-efflux system protein; Identified by similarity to SP:P03819; match to protein family HMM PF02254; match to protein family HMM TIGR00932; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.939
SPO0153
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
 
     0.879
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
    0.578
aspC-1
Aspartate aminotransferase; Identified by similarity to SP:Q06191.
  
    0.452
aspC-2
Aspartate aminotransferase; Identified by similarity to SP:Q02635; match to protein family HMM PF00155.
  
    0.452
aspC-3
Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155.
  
    0.452
SPO2144
Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.
  
    0.452
SPO2589
Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.
  
    0.452
SPO3417
Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.
  
    0.452
SPO0164
Oxidoreductase, FMN-binding/pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00724.
  
  
 0.424
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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