Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPO0165Pyrroline-5-carboxylate reductase, putative. (243 aa)    
Predicted Functional Partners:
putA
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 0.958
arcB
Ornithine cyclodeaminase; Identified by similarity to SP:P09773; match to protein family HMM PF02423.
  
 
 0.909
pip
Proline iminopeptidase; Identified by match to protein family HMM PF00561; match to protein family HMM TIGR01249; Belongs to the peptidase S33 family.
    
 0.901
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
     
  0.900
SPO0164
Oxidoreductase, FMN-binding/pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00724.
 
  
 0.853
SPO0166
N-methylproline demethylase, putative; Identified by similarity to SP:O87278; match to protein family HMM PF00724.
 
  
 0.839
SPO0167
Identified by match to protein family HMM PF06253; Belongs to the trimethylamine methyltransferase family.
       0.773
SPO0168
Transcriptional regulator, TetR family; Identified by match to protein family HMM PF00440.
 
     0.613
SPO2921
Hypothetical protein; Identified by similarity to GB:AAA70414.1.
  
     0.559
gltB
Glutamate synthase, large subunit; Identified by similarity to SP:Q05755; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898.
     
 0.548
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
Server load: low (16%) [HD]