| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO0265 | SPO0266 | SPO0265 | SPO0266 | Auxin efflux carrier family protein; Identified by similarity to GB:AAA99820.1; match to protein family HMM PF03547. | HD domain protein; Identified by match to protein family HMM PF01966. | 0.776 |
| SPO0265 | aroC | SPO0265 | SPO0267 | Auxin efflux carrier family protein; Identified by similarity to GB:AAA99820.1; match to protein family HMM PF03547. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.780 |
| SPO0265 | ribH-1 | SPO0265 | SPO0268 | Auxin efflux carrier family protein; Identified by similarity to GB:AAA99820.1; match to protein family HMM PF03547. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.475 |
| SPO0266 | SPO0265 | SPO0266 | SPO0265 | HD domain protein; Identified by match to protein family HMM PF01966. | Auxin efflux carrier family protein; Identified by similarity to GB:AAA99820.1; match to protein family HMM PF03547. | 0.776 |
| SPO0266 | SPO0269 | SPO0266 | SPO0269 | HD domain protein; Identified by match to protein family HMM PF01966. | Negative transcriptional regulator; Identified by match to protein family HMM PF04299. | 0.441 |
| SPO0266 | SPO2760 | SPO0266 | SPO2760 | HD domain protein; Identified by match to protein family HMM PF01966. | Identified by match to protein family HMM PF00753; match to protein family HMM PF07521. | 0.512 |
| SPO0266 | SPO3737 | SPO0266 | SPO3737 | HD domain protein; Identified by match to protein family HMM PF01966. | Pyridine nucleotide-disulfide oxidoreductase family protein; Identified by match to protein family HMM PF00070. | 0.446 |
| SPO0266 | aroC | SPO0266 | SPO0267 | HD domain protein; Identified by match to protein family HMM PF01966. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.784 |
| SPO0266 | gltB | SPO0266 | SPO3768 | HD domain protein; Identified by match to protein family HMM PF01966. | Glutamate synthase, large subunit; Identified by similarity to SP:Q05755; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898. | 0.469 |
| SPO0266 | nnrD | SPO0266 | SPO2293 | HD domain protein; Identified by match to protein family HMM PF01966. | YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] | 0.449 |
| SPO0266 | pheT | SPO0266 | SPO3489 | HD domain protein; Identified by match to protein family HMM PF01966. | phenylalanyl-tRNA synthetase, beta subunit; Identified by similarity to SP:P07395; match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.485 |
| SPO0266 | pnp | SPO0266 | SPO3389 | HD domain protein; Identified by match to protein family HMM PF01966. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.538 |
| SPO0266 | ribH-1 | SPO0266 | SPO0268 | HD domain protein; Identified by match to protein family HMM PF01966. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.484 |
| SPO0269 | SPO0266 | SPO0269 | SPO0266 | Negative transcriptional regulator; Identified by match to protein family HMM PF04299. | HD domain protein; Identified by match to protein family HMM PF01966. | 0.441 |
| SPO0269 | aroC | SPO0269 | SPO0267 | Negative transcriptional regulator; Identified by match to protein family HMM PF04299. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.412 |
| SPO0269 | ribH-1 | SPO0269 | SPO0268 | Negative transcriptional regulator; Identified by match to protein family HMM PF04299. | Riboflavin synthase, beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.575 |
| SPO2760 | SPO0266 | SPO2760 | SPO0266 | Identified by match to protein family HMM PF00753; match to protein family HMM PF07521. | HD domain protein; Identified by match to protein family HMM PF01966. | 0.512 |
| SPO2760 | pnp | SPO2760 | SPO3389 | Identified by match to protein family HMM PF00753; match to protein family HMM PF07521. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.490 |
| SPO3737 | SPO0266 | SPO3737 | SPO0266 | Pyridine nucleotide-disulfide oxidoreductase family protein; Identified by match to protein family HMM PF00070. | HD domain protein; Identified by match to protein family HMM PF01966. | 0.446 |
| SPO3737 | gltB | SPO3737 | SPO3768 | Pyridine nucleotide-disulfide oxidoreductase family protein; Identified by match to protein family HMM PF00070. | Glutamate synthase, large subunit; Identified by similarity to SP:Q05755; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898. | 0.690 |