Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPO0298Identified by match to protein family HMM PF00441; match to protein family HMM PF02770. (567 aa)    
Predicted Functional Partners:
dmdD
Methylthioacryloyl-CoA hydratase; Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by catalyzing both the hydration and the hydrolysis of 3-(methylthio)acryloyl-CoA (MTA-CoA) to acetaldehyde, CO2, MeSH, and CoA.
  
 0.940
SPO0677
AMP-binding protein.
 
 
 0.936
dmdB
3-methylmercaptopropionyl-CoA ligase; Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton. Catalyzes the ATP-dependent ligation of methylmercaptopropionate (MMPA) and CoA to yield methylmercaptopropionate-CoA (MMPA-CoA). It is also active with short-chain-fatty-acid (carboxylic acids up to six carbons in length) ; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
 0.919
SPO2915
Identified by match to protein family HMM PF00441; match to protein family HMM PF02770.
  
  
0.912
dmdC
3-methylmercaptopropionyl-CoA dehydrogenase; Involved in the assimilation of dimethylsulphoniopropionate (DMSP), an important compound in the fixation of carbon in marine phytoplankton, by mediating the conversion of 3-(methylthio)propanoyl- CoA (MMPA-CoA) to 3-(methylthio)acryloyl-CoA (MTA-CoA). Belongs to the acyl-CoA dehydrogenase family.
  
  
 
0.909
SPO0772
enoyl-CoA hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.869
etfA
Electron transfer flavoprotein, alpha subunit; Identified by similarity to SP:P38974.
 
 0.837
SPO0299
Identified by match to protein family HMM PF00753.
  
   0.795
fabJ-1
Fatty oxidation complex, alpha subunit; Identified by similarity to SP:P77399; match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737.
 
 0.794
SPO0300
Hypothetical protein; Identified by Glimmer2; putative.
       0.773
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
Server load: low (32%) [HD]