node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SPO1498 | SPO2932 | SPO1498 | SPO2932 | Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate dehydrogenase; Identified by similarity to SP:O30807; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | 0.987 |
SPO1498 | fumC | SPO1498 | SPO1905 | Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.981 |
SPO1498 | glcB | SPO1498 | SPO2839 | Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.938 |
SPO1498 | gltA | SPO1498 | SPO2157 | Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Citrate synthase I; Identified by similarity to SP:P00891; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | 0.988 |
SPO1498 | maeB | SPO1498 | SPO0012 | Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | NADP-dependent malic enzyme; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | 0.986 |
SPO1498 | mdh | SPO1498 | SPO0349 | Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.995 |
SPO1498 | pyc | SPO1498 | SPO1171 | Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.605 |
SPO1498 | sucC-2 | SPO1498 | SPO1568 | Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | malate--CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.937 |
SPO1498 | sucD-2 | SPO1498 | SPO1569 | Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | malate--CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.920 |
SPO1498 | tyrB | SPO1498 | SPO3720 | Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Aromatic amino acid aminotransferase; Identified by similarity to SP:P95468; match to protein family HMM PF00155. | 0.903 |
SPO2932 | SPO1498 | SPO2932 | SPO1498 | Malate dehydrogenase; Identified by similarity to SP:O30807; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.987 |
SPO2932 | fumC | SPO2932 | SPO1905 | Malate dehydrogenase; Identified by similarity to SP:O30807; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.965 |
SPO2932 | glcB | SPO2932 | SPO2839 | Malate dehydrogenase; Identified by similarity to SP:O30807; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.971 |
SPO2932 | gltA | SPO2932 | SPO2157 | Malate dehydrogenase; Identified by similarity to SP:O30807; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | Citrate synthase I; Identified by similarity to SP:P00891; match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | 0.933 |
SPO2932 | maeB | SPO2932 | SPO0012 | Malate dehydrogenase; Identified by similarity to SP:O30807; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | NADP-dependent malic enzyme; Identified by similarity to SP:O30808; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | 0.948 |
SPO2932 | mdh | SPO2932 | SPO0349 | Malate dehydrogenase; Identified by similarity to SP:O30807; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.966 |
SPO2932 | pyc | SPO2932 | SPO1171 | Malate dehydrogenase; Identified by similarity to SP:O30807; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.952 |
SPO2932 | sucC-2 | SPO2932 | SPO1568 | Malate dehydrogenase; Identified by similarity to SP:O30807; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | malate--CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.921 |
SPO2932 | sucD-2 | SPO2932 | SPO1569 | Malate dehydrogenase; Identified by similarity to SP:O30807; match to protein family HMM PF00390; match to protein family HMM PF01515; match to protein family HMM PF03949. | malate--CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.899 |
fumC | SPO1498 | SPO1905 | SPO1498 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.981 |