Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ccrAcrotonyl-CoA reductase; Identified by match to protein family HMM PF00107; match to protein family HMM TIGR01751. (428 aa)    
Predicted Functional Partners:
SPO0368
methylmalonyl-CoA mutase; Identified by similarity to SP:Q49115; match to protein family HMM PF01642; match to protein family HMM PF02310; match to protein family HMM TIGR00640; match to protein family HMM TIGR00641.
  
 0.954
SPO0932
methylmalonyl-CoA epimerase; Identified by similarity to GB:AAK52053.1; match to protein family HMM PF00903.
     
 0.938
SPO3152
MaoC domain protein; Identified by match to protein family HMM PF01575.
 
 0.937
SPO0355
Hypothetical protein; Identified by similarity to GB:AAK25618.1.
 
 
 0.875
SPO0147
enoyl-CoA hydratase; Identified by similarity to SP:P14604; match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.861
SPO0693
isobutyryl-CoA dehydrogenase; Identified by similarity to GB:AAL17673.1.
 
   0.787
prpE
propionate--CoA ligase; Identified by similarity to SP:P77495; match to protein family HMM PF00501.
 
 
  
 0.711
SPO0369
Acyltransferase family protein; Identified by similarity to SP:P00482; match to protein family HMM PF01553.
     
 0.654
SPO0849
Non-ribosomal peptide synthase; Identified by similarity to GB:CAD70195.1; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801.
  
 
 0.653
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
  
 0.634
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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