close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO0373Helicase, ATP-dependent, putative. (465 aa)    
Predicted Functional Partners:
SPO3873
ATP-dependent DNA helicase, UvrD/Rep family; Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily.
  
 
 0.914
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.865
SPO2595
Hypothetical protein; 'Novel gene detected by proteogenomics, SPO_PG035; identified in over 20 other Roseobacter strains'.
  
  
 0.795
SPO1243
Hypothetical protein; Identified by similarity to GB:AAR38391.1.
  
     0.775
recQ
ATP-dependent DNA helicase RecQ; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389.
  
 
 0.764
SPO0896
Hypothetical protein; Identified by similarity to GB:AAK25555.1.
  
     0.762
SPO0951
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.743
SPO0372
Autoinducer synthesis protein; Identified by match to protein family HMM PF00765.
 
   
 0.742
SPO3336
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.738
SPO0081
Hypothetical protein; Identified by similarity to GB:AAM48708.1.
  
     0.725
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
Server load: medium (44%) [HD]