| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO0398 | SPO0400 | SPO0398 | SPO0400 | Hypothetical protein; Identified by similarity to GB:BAC45936.1. | Hypothetical protein; Identified by similarity to GB:AAN66948.1; match to protein family HMM PF02021; Belongs to the UPF0102 family. | 0.732 |
| SPO0398 | glnD | SPO0398 | SPO0397 | Hypothetical protein; Identified by similarity to GB:BAC45936.1. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.749 |
| SPO0398 | gshB | SPO0398 | SPO0401 | Hypothetical protein; Identified by similarity to GB:BAC45936.1. | Glutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. | 0.657 |
| SPO0398 | rsmI | SPO0398 | SPO0399 | Hypothetical protein; Identified by similarity to GB:BAC45936.1. | Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.768 |
| SPO0400 | SPO0398 | SPO0400 | SPO0398 | Hypothetical protein; Identified by similarity to GB:AAN66948.1; match to protein family HMM PF02021; Belongs to the UPF0102 family. | Hypothetical protein; Identified by similarity to GB:BAC45936.1. | 0.732 |
| SPO0400 | glnD | SPO0400 | SPO0397 | Hypothetical protein; Identified by similarity to GB:AAN66948.1; match to protein family HMM PF02021; Belongs to the UPF0102 family. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.660 |
| SPO0400 | gshB | SPO0400 | SPO0401 | Hypothetical protein; Identified by similarity to GB:AAN66948.1; match to protein family HMM PF02021; Belongs to the UPF0102 family. | Glutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. | 0.753 |
| SPO0400 | rsmI | SPO0400 | SPO0399 | Hypothetical protein; Identified by similarity to GB:AAN66948.1; match to protein family HMM PF02021; Belongs to the UPF0102 family. | Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.861 |
| alr | rsmI | SPO2670 | SPO0399 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.538 |
| ftsZ | rnhB | SPO1204 | SPO3452 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.550 |
| ftsZ | rsmI | SPO1204 | SPO0399 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.692 |
| gidB | rlmH | SPO0002 | SPO0220 | Glucose-inhibited division protein B; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | Hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.406 |
| gidB | rsmI | SPO0002 | SPO0399 | Glucose-inhibited division protein B; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.589 |
| glnD | SPO0398 | SPO0397 | SPO0398 | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | Hypothetical protein; Identified by similarity to GB:BAC45936.1. | 0.749 |
| glnD | SPO0400 | SPO0397 | SPO0400 | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | Hypothetical protein; Identified by similarity to GB:AAN66948.1; match to protein family HMM PF02021; Belongs to the UPF0102 family. | 0.660 |
| glnD | gshB | SPO0397 | SPO0401 | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | Glutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. | 0.585 |
| glnD | rsmI | SPO0397 | SPO0399 | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | Tetrapyrrole methylase family protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.660 |
| gshB | SPO0398 | SPO0401 | SPO0398 | Glutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. | Hypothetical protein; Identified by similarity to GB:BAC45936.1. | 0.657 |
| gshB | SPO0400 | SPO0401 | SPO0400 | Glutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. | Hypothetical protein; Identified by similarity to GB:AAN66948.1; match to protein family HMM PF02021; Belongs to the UPF0102 family. | 0.753 |
| gshB | glnD | SPO0401 | SPO0397 | Glutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. | protein-P-II uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.585 |