Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
gshBGlutathione synthetase; Identified by similarity to SP:P04425; match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. (310 aa)    
Predicted Functional Partners:
gor
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
  
  
 0.950
gshA
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
    
 0.947
pepA
Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
 
 0.946
SPO3764
Identified by match to protein family HMM PF02798.
 
  
 0.946
SPO3742
Glutathione peroxidase famly protein; Identified by match to protein family HMM PF00255; Belongs to the glutathione peroxidase family.
    
 0.938
SPO3306
Glutathione S-transferase, putative; Identified by similarity to GB:AAC44159.1; match to protein family HMM PF00043; match to protein family HMM PF02798.
 
  
 0.935
gst
Glutathione S-transferase; Identified by similarity to SP:P39100; match to protein family HMM PF00043; match to protein family HMM PF02798; Belongs to the GST superfamily.
 
  
 0.934
SPO2209
Glutamate--cysteine ligase family protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
    
 0.926
SPO3717
Identified by match to protein family HMM PF00883; Belongs to the peptidase M17 family.
  
 
 0.925
SPO1324
Identified by match to protein family HMM PF02798.
 
  
 0.924
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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