STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO0578acetyl-CoA carboxylase carboxyltransferase; Identified by similarity to GB:BAB16296.1. (539 aa)    
Predicted Functional Partners:
SPO0579
acetyl-CoA carboxylase, biotin carboxylase, putative; Identified by similarity to GB:BAB16297.1.
 0.998
accC
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.964
SPO2540
Carbamoyl-phosphate synthase, putative; Identified by match to protein family HMM PF00289; match to protein family HMM PF02785; match to protein family HMM PF02786.
 
 0.954
mccA
methylcrotonyl-CoA carboxylase, alpha subunit; Identified by similarity to SP:Q96RQ3; match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786.
 0.936
SPO0577
Hypothetical protein; Identified by similarity to PIR:D83286.
 
  
 0.892
pccA
propionyl-CoA carboxylase, alpha subunit; This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA. Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then tranfers the carboxyl group from carboxylated biotin to propionyl-CoA (Probable).
 
 0.888
SPO0580
Oxidoreductase, 2-nitropropane dioxygenase family.
 
    0.815
mvaB
hydroxymethylglutaryl-CoA lyase; Identified by similarity to SP:P13703; match to protein family HMM PF00682.
 
 0.798
SPO0581
Hypothetical protein; Identified by similarity to GB:CAB95889.1.
       0.783
acdA-1
acyl-CoA dehydrogenase.
  
 0.688
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.