Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SPO0725Bacterial SH3 domain family protein. (211 aa)    
Predicted Functional Partners:
SPO2471
Acetyltransferase, GNAT family; Identified by match to protein family HMM PF00583.
  
    0.697
SPO0724
Oxidoreductase, short-chain dehydrogenase/reductase family; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.653
SPO3279
NUDIX domain protein; Identified by match to protein family HMM PF00293.
 
     0.628
SPO0286
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.605
SPO0905
Hypothetical protein; Identified by similarity to PIR:T03518.
  
     0.599
SPO1866
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.595
SPO1332
Hypothetical protein; Identified by similarity to GB:BAB48824.1.
  
     0.581
SPO3441
Hypothetical protein; Identified by similarity to GB:AAC02256.1.
  
     0.551
SPO0460
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.549
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
       0.546
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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