Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPO0791M23/M37 peptidase/aminotransferase, class III; Identified by match to protein family HMM PF00202; match to protein family HMM PF01551. (1018 aa)    
Predicted Functional Partners:
SPO0849
Non-ribosomal peptide synthase; Identified by similarity to GB:CAD70195.1; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF00975; match to protein family HMM PF02801.
  
 
 0.740
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.693
SPO3035
Aspartate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.
  
  
 0.691
SPO3380
Gamma-butyrobetaine hydroxylase, putative; Identified by similarity to SP:P80193; match to protein family HMM PF03322.
 
  
 0.675
SPO0847
Non-ribosomal peptide synthetase; Identified by similarity to GB:CAC01603.1; match to protein family HMM PF00296; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00551; match to protein family HMM PF02911; match to protein family HMM TIGR01733.
  
  
 0.673
nadE
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.638
SPO3038
Sensor histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
  
 
 0.637
SPO3687
Decarboxylase, pyridoxal-dependent; Identified by match to protein family HMM PF00282.
  
 
 0.633
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.632
SPO0055
OmpA domain protein; Identified by match to protein family HMM PF00691.
  
  
 0.628
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
Server load: low (28%) [HD]