close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cueRCu(I)-responsive transcriptional regulator; Identified by match to protein family HMM PF00376; match to protein family HMM TIGR02044. (129 aa)    
Predicted Functional Partners:
SPO0794
Copper-translocating P-type ATPase; Identified by similarity to SP:P37279; match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525.
  
 0.938
SPO0960
Transcriptional regulator, MerR family; Identified by match to protein family HMM PF00376.
  
     0.703
rpoD
RNA polymerase sigma-70 factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.625
SPO0797
Bile acid transporter family protein; Identified by match to protein family HMM PF01758.
  
    0.563
SPO0795
Oxidoreductase, short chain dehydrogenase/reductase family; Identified by similarity to PIR:E83152; match to protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.559
SPO0796
Hypothetical protein; Identified by similarity to GB:BAC72444.1.
     
 0.557
SPO0798
Monooxygenase domain protein; Identified by similarity to GB:AAS47561.1.
       0.551
SPO0792
6-phosphogluconate dehydrogenase domain protein; Identified by match to protein family HMM PF03446; match to protein family HMM TIGR00872; match to protein family HMM TIGR00873.
       0.533
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.444
SPO2850
DnaJ domain protein; Identified by match to protein family HMM PF00226.
  
 
 0.444
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.