| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO0805 | ihfB | SPO0805 | SPO0804 | Hypothetical protein; Identified by similarity to GB:CAE25511.1. | Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.861 |
| SPO0805 | trpB | SPO0805 | SPO0808 | Hypothetical protein; Identified by similarity to GB:CAE25511.1. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.621 |
| SPO0805 | trpF | SPO0805 | SPO0806 | Hypothetical protein; Identified by similarity to GB:CAE25511.1. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by similarity to SP:Q56320; match to protein family HMM PF00697; Belongs to the TrpF family. | 0.873 |
| hisF | trpA | SPO1156 | SPO0815 | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.538 |
| hisF | trpB | SPO1156 | SPO0808 | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.538 |
| hisF | trpC | SPO1156 | SPO2151 | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Indole-3-glycerol phosphate synthase; Identified by similarity to SP:P20577; match to protein family HMM PF00218; Belongs to the TrpC family. | 0.544 |
| hisF | trpE | SPO1156 | SPO2146 | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.658 |
| hisF | trpF | SPO1156 | SPO0806 | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by similarity to SP:Q56320; match to protein family HMM PF00697; Belongs to the TrpF family. | 0.538 |
| ihfB | SPO0805 | SPO0804 | SPO0805 | Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | Hypothetical protein; Identified by similarity to GB:CAE25511.1. | 0.861 |
| ihfB | trpB | SPO0804 | SPO0808 | Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.663 |
| ihfB | trpF | SPO0804 | SPO0806 | Integration host factor, beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by similarity to SP:Q56320; match to protein family HMM PF00697; Belongs to the TrpF family. | 0.867 |
| pabB | trpA | SPO0924 | SPO0815 | Para-aminobenzoate synthase component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.911 |
| pabB | trpB | SPO0924 | SPO0808 | Para-aminobenzoate synthase component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.932 |
| pabB | trpC | SPO0924 | SPO2151 | Para-aminobenzoate synthase component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Indole-3-glycerol phosphate synthase; Identified by similarity to SP:P20577; match to protein family HMM PF00218; Belongs to the TrpC family. | 0.989 |
| pabB | trpD | SPO0924 | SPO2150 | Para-aminobenzoate synthase component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.989 |
| pabB | trpE | SPO0924 | SPO2146 | Para-aminobenzoate synthase component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.850 |
| pabB | trpF | SPO0924 | SPO0806 | Para-aminobenzoate synthase component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | N-(5'phosphoribosyl)anthranilate isomerase; Identified by similarity to SP:Q56320; match to protein family HMM PF00697; Belongs to the TrpF family. | 0.930 |
| pabB | trpG | SPO0924 | SPO2149 | Para-aminobenzoate synthase component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | Anthranilate synthase component II; Identified by similarity to PIR:A01122; match to protein family HMM PF00117; match to protein family HMM TIGR00566. | 0.999 |
| trpA | hisF | SPO0815 | SPO1156 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.538 |
| trpA | pabB | SPO0815 | SPO0924 | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Para-aminobenzoate synthase component I; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553. | 0.911 |