STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPO0917Identified by match to protein family HMM PF00903. (125 aa)    
Predicted Functional Partners:
SPO1270
Lactoylglutathione lyase, putative; Identified by match to protein family HMM PF00903.
  
 
  0.901
SPO0415
D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF02826.
    
  0.900
gloB
Hydroxyacylglutathione hydrolase, putative; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
     
  0.900
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
  0.800
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.800
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.800
SPO1142
Threonine dehydratase, putative; Identified by match to protein family HMM PF00291.
     
  0.800
sdaA
L-serine ammonia-lyase; Identified by similarity to SP:O53614; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.800
SPO3341
Pyridoxal-phosphate dependent enzyme family protein; Identified by match to protein family HMM PF00291.
     
  0.800
SPO0916
Hypothetical protein; Identified by similarity to GB:AAS41921.1.
       0.464
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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