Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SPO0932methylmalonyl-CoA epimerase; Identified by similarity to GB:AAK52053.1; match to protein family HMM PF00903. (136 aa)    
Predicted Functional Partners:
SPO1105
methylmalonyl-CoA mutase; Identified by similarity to SP:O86028; match to protein family HMM PF01642; match to protein family HMM PF02310; match to protein family HMM TIGR00640; match to protein family HMM TIGR00641.
 
  
 0.988
SPO0368
methylmalonyl-CoA mutase; Identified by similarity to SP:Q49115; match to protein family HMM PF01642; match to protein family HMM PF02310; match to protein family HMM TIGR00640; match to protein family HMM TIGR00641.
 
  
 0.987
pccB
propionyl-CoA carboxylase, beta subunit; Identified by similarity to PIR:T42208; match to protein family HMM PF01039.
 
 
 0.979
ccrA
crotonyl-CoA reductase; Identified by match to protein family HMM PF00107; match to protein family HMM TIGR01751.
     
 0.938
pccA
propionyl-CoA carboxylase, alpha subunit; This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA. Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then tranfers the carboxyl group from carboxylated biotin to propionyl-CoA (Probable).
 
 
 0.938
SPO0973
LAO/AO transport system ATPase; Identified by similarity to SP:P27254; match to protein family HMM PF03308; match to protein family HMM TIGR00750.
 
     0.792
SPO2541
propionyl-CoA carboxylase, putative; Identified by similarity to GB:AAD28194.1; match to protein family HMM PF01039.
 
 
 0.791
SPO0933
Hypothetical protein; Identified by similarity to GB:BAB48740.1.
       0.762
hmgA
Homogentisate 1,2-dioxygenase; Identified by similarity to SP:Q9X4F5.
  
 
 0.749
SPO0931
Response regulator; Identified by match to protein family HMM PF00072.
       0.620
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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