STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobB-2CobB; Identified by similarity to GB:AAC78722.1; match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily. (232 aa)    
Predicted Functional Partners:
nadE
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 0.962
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.942
nadK
ATP-NAD kinase, putative; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.939
deoD
Purine nucleoside phosphorylase; Identified by similarity to SP:O34925; match to protein family HMM PF01048; match to protein family HMM TIGR00107.
    
 0.928
pncA
Pyrazinamidase/nicotinamidase; Identified by similarity to SP:P21369; match to protein family HMM PF00857.
  
 0.916
sthA
Soluble pyridine nucleotide transhydrogenase; Identified by similarity to SP:P27306; match to protein family HMM PF00070; match to protein family HMM PF02852.
  
 0.916
iunH
Inosine-uridine preferring nucleoside hydrolase; Identified by match to protein family HMM PF01156.
   
 
 0.909
pntA
NAD(P) transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family.
    
 0.909
SPO3541
Hydrolase, NUDIX family; Identified by match to protein family HMM PF00293.
    
 0.908
SPO2469
Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444.
    
  0.902
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.