node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SPO0115 | SPO1565 | SPO0115 | SPO1565 | maoC family protein/phosphate acetyl/butaryl transferase; Identified by match to protein family HMM PF01515; match to protein family HMM PF01575. | Citrate lyase, putative; Identified by similarity to SP:O53078; Belongs to the HpcH/HpaI aldolase family. | 0.919 |
SPO0115 | acs | SPO0115 | SPO1813 | maoC family protein/phosphate acetyl/butaryl transferase; Identified by match to protein family HMM PF01515; match to protein family HMM PF01575. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.938 |
SPO0115 | acsA | SPO0115 | SPO2791 | maoC family protein/phosphate acetyl/butaryl transferase; Identified by match to protein family HMM PF01515; match to protein family HMM PF01575. | Acetyl-coenzyme A synthetase; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | 0.938 |
SPO0115 | mclA | SPO0115 | SPO3608 | maoC family protein/phosphate acetyl/butaryl transferase; Identified by match to protein family HMM PF01515; match to protein family HMM PF01575. | malyl-CoA lyase; Identified by similarity to GB:AAB58884.1; match to protein family HMM TIGR01588; Belongs to the HpcH/HpaI aldolase family. | 0.919 |
SPO0115 | mmsA | SPO0115 | SPO2203 | maoC family protein/phosphate acetyl/butaryl transferase; Identified by match to protein family HMM PF01515; match to protein family HMM PF01575. | Methylmalonate-semialdehyde dehydrogenase; Identified by similarity to SP:P28810; match to protein family HMM PF00171; match to protein family HMM TIGR01722. | 0.922 |
SPO0115 | pccA | SPO0115 | SPO1101 | maoC family protein/phosphate acetyl/butaryl transferase; Identified by match to protein family HMM PF01515; match to protein family HMM PF01575. | propionyl-CoA carboxylase, alpha subunit; This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA. Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then tranfers the carboxyl group from carboxylated biotin to propionyl-CoA (Probable). | 0.915 |
SPO0115 | pccB | SPO0115 | SPO1094 | maoC family protein/phosphate acetyl/butaryl transferase; Identified by match to protein family HMM PF01515; match to protein family HMM PF01575. | propionyl-CoA carboxylase, beta subunit; Identified by similarity to PIR:T42208; match to protein family HMM PF01039. | 0.923 |
SPO0932 | SPO2541 | SPO0932 | SPO2541 | methylmalonyl-CoA epimerase; Identified by similarity to GB:AAK52053.1; match to protein family HMM PF00903. | propionyl-CoA carboxylase, putative; Identified by similarity to GB:AAD28194.1; match to protein family HMM PF01039. | 0.792 |
SPO0932 | mccB | SPO0932 | SPO2790 | methylmalonyl-CoA epimerase; Identified by similarity to GB:AAK52053.1; match to protein family HMM PF00903. | methylcrotonyl-CoA carboxylase, beta subunit; Identified by similarity to SP:Q9HCC0; match to protein family HMM PF01039. | 0.420 |
SPO0932 | pccA | SPO0932 | SPO1101 | methylmalonyl-CoA epimerase; Identified by similarity to GB:AAK52053.1; match to protein family HMM PF00903. | propionyl-CoA carboxylase, alpha subunit; This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA. Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then tranfers the carboxyl group from carboxylated biotin to propionyl-CoA (Probable). | 0.956 |
SPO0932 | pccB | SPO0932 | SPO1094 | methylmalonyl-CoA epimerase; Identified by similarity to GB:AAK52053.1; match to protein family HMM PF00903. | propionyl-CoA carboxylase, beta subunit; Identified by similarity to PIR:T42208; match to protein family HMM PF01039. | 0.979 |
SPO1565 | SPO0115 | SPO1565 | SPO0115 | Citrate lyase, putative; Identified by similarity to SP:O53078; Belongs to the HpcH/HpaI aldolase family. | maoC family protein/phosphate acetyl/butaryl transferase; Identified by match to protein family HMM PF01515; match to protein family HMM PF01575. | 0.919 |
SPO1565 | acs | SPO1565 | SPO1813 | Citrate lyase, putative; Identified by similarity to SP:O53078; Belongs to the HpcH/HpaI aldolase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.906 |
SPO1565 | acsA | SPO1565 | SPO2791 | Citrate lyase, putative; Identified by similarity to SP:O53078; Belongs to the HpcH/HpaI aldolase family. | Acetyl-coenzyme A synthetase; Identified by similarity to SP:P39062; match to protein family HMM PF00501. | 0.906 |
SPO1565 | mclA | SPO1565 | SPO3608 | Citrate lyase, putative; Identified by similarity to SP:O53078; Belongs to the HpcH/HpaI aldolase family. | malyl-CoA lyase; Identified by similarity to GB:AAB58884.1; match to protein family HMM TIGR01588; Belongs to the HpcH/HpaI aldolase family. | 0.903 |
SPO1565 | mmsA | SPO1565 | SPO2203 | Citrate lyase, putative; Identified by similarity to SP:O53078; Belongs to the HpcH/HpaI aldolase family. | Methylmalonate-semialdehyde dehydrogenase; Identified by similarity to SP:P28810; match to protein family HMM PF00171; match to protein family HMM TIGR01722. | 0.807 |
SPO1565 | pccA | SPO1565 | SPO1101 | Citrate lyase, putative; Identified by similarity to SP:O53078; Belongs to the HpcH/HpaI aldolase family. | propionyl-CoA carboxylase, alpha subunit; This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA. Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then tranfers the carboxyl group from carboxylated biotin to propionyl-CoA (Probable). | 0.917 |
SPO1565 | pccB | SPO1565 | SPO1094 | Citrate lyase, putative; Identified by similarity to SP:O53078; Belongs to the HpcH/HpaI aldolase family. | propionyl-CoA carboxylase, beta subunit; Identified by similarity to PIR:T42208; match to protein family HMM PF01039. | 0.908 |
SPO2541 | SPO0932 | SPO2541 | SPO0932 | propionyl-CoA carboxylase, putative; Identified by similarity to GB:AAD28194.1; match to protein family HMM PF01039. | methylmalonyl-CoA epimerase; Identified by similarity to GB:AAK52053.1; match to protein family HMM PF00903. | 0.792 |
SPO2541 | pccA | SPO2541 | SPO1101 | propionyl-CoA carboxylase, putative; Identified by similarity to GB:AAD28194.1; match to protein family HMM PF01039. | propionyl-CoA carboxylase, alpha subunit; This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), the enzyme catalyzing the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl- CoA/(S)-methylmalonyl-CoA. Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then tranfers the carboxyl group from carboxylated biotin to propionyl-CoA (Probable). | 0.960 |