| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SPO0572 | SPO3650 | SPO0572 | SPO3650 | Adenylate/guanylate cyclase. | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | 0.536 |
| SPO0572 | cpdA | SPO0572 | SPO1176 | Adenylate/guanylate cyclase. | Ser/Thr protein phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.913 |
| SPO0572 | cpdA-2 | SPO0572 | SPO1819 | Adenylate/guanylate cyclase. | Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.913 |
| SPO0751 | SPO3650 | SPO0751 | SPO3650 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | 0.613 |
| SPO0751 | cpdA | SPO0751 | SPO1176 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | Ser/Thr protein phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.904 |
| SPO0751 | cpdA-2 | SPO0751 | SPO1819 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.904 |
| SPO0901 | SPO3650 | SPO0901 | SPO3650 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00111; match to protein family HMM PF00211. | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | 0.531 |
| SPO0901 | cpdA | SPO0901 | SPO1176 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00111; match to protein family HMM PF00211. | Ser/Thr protein phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.905 |
| SPO0901 | cpdA-2 | SPO0901 | SPO1819 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00111; match to protein family HMM PF00211. | Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.905 |
| SPO2904 | amn | SPO2904 | SPO3745 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. | 0.900 |
| SPO2904 | apt | SPO2904 | SPO3066 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.911 |
| SPO2904 | cpdA | SPO2904 | SPO1176 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Ser/Thr protein phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.908 |
| SPO2904 | cpdA-2 | SPO2904 | SPO1819 | Ser/Thr protein phosphatase/nucleotidase, putative; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.908 |
| SPO3450 | SPO3455 | SPO3450 | SPO3455 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF04248. | 0.429 |
| SPO3450 | SPO3650 | SPO3450 | SPO3650 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | 0.630 |
| SPO3450 | cpdA | SPO3450 | SPO1176 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | Ser/Thr protein phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.913 |
| SPO3450 | cpdA-2 | SPO3450 | SPO1819 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | Phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.913 |
| SPO3455 | SPO3450 | SPO3455 | SPO3450 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF04248. | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | 0.429 |
| SPO3455 | SPO3650 | SPO3455 | SPO3650 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF04248. | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211. | 0.534 |
| SPO3455 | cpdA | SPO3455 | SPO1176 | Adenylate/guanylate cyclase; Identified by match to protein family HMM PF00211; match to protein family HMM PF04248. | Ser/Thr protein phosphatase family protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.904 |