Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SPO1224Hypothetical protein; Identified by similarity to GB:BAB66386.1. (387 aa)    
Predicted Functional Partners:
SPO1222
Site-specific recombinase, resolvase family; Identified by match to protein family HMM PF00239; match to protein family HMM PF07508.
 
    0.852
SPO1223
Hypothetical protein; Identified by Glimmer2; putative.
       0.727
SPO2408
Hypothetical protein; Identified by Glimmer2; putative.
 
    0.718
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.568
nusG
Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination.
  
     0.568
SPO2123
Identified by match to protein family HMM PF01844.
   
 
 0.538
SPO3438
Hypothetical protein; Identified by similarity to GB:CAD55640.1.
   
 
 0.538
SPO1194
Cell division protein FtsW; Identified by similarity to SP:P16457; match to protein family HMM PF01098; Belongs to the SEDS family.
 
     0.524
SPO1225
Hypothetical protein; Identified by similarity to GB:AAQ58890.1.
       0.522
ssb
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
 
   
 0.498
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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