STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ispZIntracellular septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (203 aa)    
Predicted Functional Partners:
SPO1337
Membrane protein, putative; Identified by match to protein family HMM PF00892.
     
 0.823
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
       0.731
SPO1337a
Hypothetical protein; 'Novel gene detected by proteogenomics, SPO_PG023; not identified in other Roseobacter strains'.
       0.630
SPO3807
Hypothetical protein; Identified by similarity to GB:BAC45729.1.
 
     0.606
SPO1335
Transcriptional regulator, Crp/Fnr family; Identified by match to protein family HMM PF00027; match to protein family HMM PF00325.
       0.575
SPO3348
Hypothetical protein; Identified by similarity to GB:CAD85590.1.
 
     0.499
atpE
ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
     0.496
SPO3567
Identified by match to protein family HMM PF00445; Belongs to the RNase T2 family.
  
     0.469
SPO1678
Hypothetical protein; Identified by similarity to PIR:AE3305.
  
     0.459
SPO2330
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.457
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.