Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hppD4-hydroxyphenylpyruvate dioxygenase; Identified by similarity to SP:P80064; match to protein family HMM PF00903; match to protein family HMM TIGR01263. (366 aa)    
Predicted Functional Partners:
hmgA
Homogentisate 1,2-dioxygenase; Identified by similarity to SP:Q9X4F5.
 
 0.996
tyrB
Aromatic amino acid aminotransferase; Identified by similarity to SP:P95468; match to protein family HMM PF00155.
  
 
 0.950
aspC-1
Aspartate aminotransferase; Identified by similarity to SP:Q06191.
   
 
 0.910
aspC-2
Aspartate aminotransferase; Identified by similarity to SP:Q02635; match to protein family HMM PF00155.
   
 
 0.910
SPO1468
Identified by match to protein family HMM PF00155.
    
 0.907
hisC-2
Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
    
 0.907
SPO3027
Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.
    
 0.907
hisC
Histidinol-phosphate aminotransferase; Identified by similarity to SP:P17736; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
    
 0.907
SPO3666
Oxidoreductase, FAD-binding protein; Identified by match to protein family HMM PF01266.
   
 
 0.906
SPO1603
Identified by match to protein family HMM PF02615; Belongs to the LDH2/MDH2 oxidoreductase family.
    
 0.902
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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