STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hisC-2Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (360 aa)    
Predicted Functional Partners:
hisB
Imidazoleglycerol-phosphate dehydratase; Identified by similarity to SP:P18787; match to protein family HMM PF00475.
 
 0.997
SPO3176
Prephenate dehydrogenase; Identified by similarity to SP:Q04983; match to protein family HMM PF02153.
 
 
 0.950
SPO3604
D-amino acid aminotransferase, putative; Identified by similarity to PIR:A31422; match to protein family HMM PF01063.
  
 
 0.915
SPO3539
Prephenate dehydratase; Identified by similarity to PIR:AC3490; match to protein family HMM PF00800.
  
 
 0.913
hppD
4-hydroxyphenylpyruvate dioxygenase; Identified by similarity to SP:P80064; match to protein family HMM PF00903; match to protein family HMM TIGR01263.
    
 0.907
SPO3687
Decarboxylase, pyridoxal-dependent; Identified by match to protein family HMM PF00282.
    
 0.903
SPO1405
Tyrosinase domain protein; Identified by match to protein family HMM PF00264.
     
  0.900
SPO1603
Identified by match to protein family HMM PF02615; Belongs to the LDH2/MDH2 oxidoreductase family.
     
  0.900
SPO3666
Oxidoreductase, FAD-binding protein; Identified by match to protein family HMM PF01266.
   
 
  0.900
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
  
 0.876
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.