node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SPO1142 | SPO1431 | SPO1142 | SPO1431 | Threonine dehydratase, putative; Identified by match to protein family HMM PF00291. | O-acetylhomoserine aminocarboxypropyltransferase; Identified by similarity to GB:BAB68505.1; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | 0.810 |
SPO1142 | SPO3341 | SPO1142 | SPO3341 | Threonine dehydratase, putative; Identified by match to protein family HMM PF00291. | Pyridoxal-phosphate dependent enzyme family protein; Identified by match to protein family HMM PF00291. | 0.924 |
SPO1142 | ilvA | SPO1142 | SPO0020 | Threonine dehydratase, putative; Identified by match to protein family HMM PF00291. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.927 |
SPO1142 | metA | SPO1142 | SPO1729 | Threonine dehydratase, putative; Identified by match to protein family HMM PF00291. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.818 |
SPO1142 | metZ | SPO1142 | SPO1351 | Threonine dehydratase, putative; Identified by match to protein family HMM PF00291. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.822 |
SPO1142 | sdaA | SPO1142 | SPO1323 | Threonine dehydratase, putative; Identified by match to protein family HMM PF00291. | L-serine ammonia-lyase; Identified by similarity to SP:O53614; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.920 |
SPO1431 | SPO1142 | SPO1431 | SPO1142 | O-acetylhomoserine aminocarboxypropyltransferase; Identified by similarity to GB:BAB68505.1; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | Threonine dehydratase, putative; Identified by match to protein family HMM PF00291. | 0.810 |
SPO1431 | SPO3341 | SPO1431 | SPO3341 | O-acetylhomoserine aminocarboxypropyltransferase; Identified by similarity to GB:BAB68505.1; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | Pyridoxal-phosphate dependent enzyme family protein; Identified by match to protein family HMM PF00291. | 0.810 |
SPO1431 | hom | SPO1431 | SPO1734 | O-acetylhomoserine aminocarboxypropyltransferase; Identified by similarity to GB:BAB68505.1; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | Homoserine dehydrogenase; Identified by similarity to SP:P08499; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | 0.893 |
SPO1431 | ilvA | SPO1431 | SPO0020 | O-acetylhomoserine aminocarboxypropyltransferase; Identified by similarity to GB:BAB68505.1; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.810 |
SPO1431 | metA | SPO1431 | SPO1729 | O-acetylhomoserine aminocarboxypropyltransferase; Identified by similarity to GB:BAB68505.1; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.987 |
SPO1431 | metZ | SPO1431 | SPO1351 | O-acetylhomoserine aminocarboxypropyltransferase; Identified by similarity to GB:BAB68505.1; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.934 |
SPO1862 | hom | SPO1862 | SPO1734 | metFprotein-like protein; Identified by similarity to PIR:B97532. | Homoserine dehydrogenase; Identified by similarity to SP:P08499; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. | 0.485 |
SPO1862 | metA | SPO1862 | SPO1729 | metFprotein-like protein; Identified by similarity to PIR:B97532. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.849 |
SPO1862 | metF | SPO1862 | SPO3016 | metFprotein-like protein; Identified by similarity to PIR:B97532. | 5,10-methylenetetrahydrofolate reductase; Identified by similarity to SP:P00394; match to protein family HMM PF02219; match to protein family HMM TIGR00676; Belongs to the methylenetetrahydrofolate reductase family. | 0.936 |
SPO1862 | metZ | SPO1862 | SPO1351 | metFprotein-like protein; Identified by similarity to PIR:B97532. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.589 |
SPO3341 | SPO1142 | SPO3341 | SPO1142 | Pyridoxal-phosphate dependent enzyme family protein; Identified by match to protein family HMM PF00291. | Threonine dehydratase, putative; Identified by match to protein family HMM PF00291. | 0.924 |
SPO3341 | SPO1431 | SPO3341 | SPO1431 | Pyridoxal-phosphate dependent enzyme family protein; Identified by match to protein family HMM PF00291. | O-acetylhomoserine aminocarboxypropyltransferase; Identified by similarity to GB:BAB68505.1; match to protein family HMM PF01053; match to protein family HMM TIGR01326. | 0.810 |
SPO3341 | ilvA | SPO3341 | SPO0020 | Pyridoxal-phosphate dependent enzyme family protein; Identified by match to protein family HMM PF00291. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.923 |
SPO3341 | metA | SPO3341 | SPO1729 | Pyridoxal-phosphate dependent enzyme family protein; Identified by match to protein family HMM PF00291. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.818 |