Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
homHomoserine dehydrogenase; Identified by similarity to SP:P08499; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. (428 aa)    
Predicted Functional Partners:
SPO3035
Aspartate kinase, monofunctional class; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family.
 
 0.994
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 0.980
thrC
Threonine synthase; Identified by similarity to GB:CAA82670.1; match to protein family HMM PF00291; match to protein family HMM TIGR00260.
 
 
 0.949
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
 
 0.948
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.944
SPO1701
Identified by match to protein family HMM PF00701; Belongs to the DapA family.
 
 
 0.929
doeC
Aspartate-semialdehyde dehydrogenase; Identified by similarity to SP:P25526; match to protein family HMM PF00171; match to protein family HMM TIGR01780.
   
 0.925
doeD
Diaminobutyric acid transaminase; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.918
SPO2882
Identified by match to protein family HMM PF00701; Belongs to the DapA family.
  
 
 0.914
SPO1863
Pterin-binding enzyme domain protein; Identified by match to protein family HMM PF00809.
  
 
 0.901
Your Current Organism:
Ruegeria pomeroyi
NCBI taxonomy Id: 246200
Other names: R. pomeroyi DSS-3, Ruegeria pomeroyi DSS-3, Ruegeria pomeroyi str. DSS-3, Ruegeria pomeroyi strain DSS-3, Silicibacter pomeroyi DSS-3
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